Kary Mullis

1944–2019 · USA · Inventor of PCR.

Contribution

In 1983, invented the polymerase chain reaction — enzymatic amplification of specific DNA segments — a bedrock of modern molecular diagnostics and research.

Why It Still Matters

Clinical virology/bacteriology panels, genotyping, and much of AMR gene detection depend on PCR logic. Extensions include Reverse Transcription Polymerase Chain Reaction (RT-PCR).

Active Recall

  1. What problem does PCR solve in one sentence?
  2. Why does PCR positivity still need clinical interpretation?